Alfred Stieglitz is perhaps best known for his spiritually rich photographs of his surroundings, family, friends, and the many women he loved, including his second wife, painter Georgia O'Keeffe. But his influence went beyond his own individual artistry. At his gallery 291 he presented the first American exhibitions of Cezanne, Matisse, Picasso, Toulouse-Lautrec, and Rousseau. His militant advocacy of photography as art won widespread acclaim for the medium.